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Although in vitro fertilization (IVF) has been available for more than 30 years, estimates of the overall chances of having a baby with IVF are lacking. To estimate the likelihood of live birth with IVF, clinicians retrospectively studied outcomes among >6000 women who were undergoing their first fresh-embryo, non-donor IVF cycles from 2000 through 2005. All patients were followed for ≤6 IVF cycles (until treatment discontinuation or delivery of live infants).
The cumulative live-birth rate after six cycles was 72% based on “optimistic” analysis (which assumed that patients who did not return for subsequent IVF cycles would have the same chances of pregnancy as would those who did return), and 51% based on “conservative” analysis (which assu…