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Most weight-loss diets claim unique nutrient compositions that guarantee unusually rapid and effortless success. Comparative studies — usually with small populations and short follow-ups — have yielded widely disparate results. Now, a large long-term multisite study suggests that all these diets result in similar outcomes.
Researchers randomized 811 overweight adults (81% white; 62% female; 69% college graduates; mean body-mass index, 33 kg/m2) to four restricted-calorie eating plans:
High fat, high protein
High fat, average protein
Low fat, high protein
Low fat, average protein
Carbohydrate intake ranged from 35% (in the first plan) to 65% (in the fourth) of total calories. All meals were prepared at home, and participants ate from a single menu…