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In two studies, researchers examined the importance of elevated central venous pressure (CVP) in patients with so-called cardiorenal syndromes, which are characterized by both heart failure (HF) and renal insufficiency (RI).
Investigators retrospectively studied 2557 patients who underwent right-heart catheterization at a single center in the Netherlands during a 17-year period to determine the association of CVP, renal function, and mortality. CVP was related inversely to both cardiac index and renal function (assessed by estimated glomerular filtration rate). During a median follow-up of 10.7 years, 29% of patients died. In a multivariate analysis, elevated CVP remained an independent predictor of mortality (hazard ratio, 1.03 per mm Hg in…