Importance of Elevated Venous Pressures in Cardiorenal Syndromes

Elevated CVP was associated with poorer outcomes in two different patient cohorts.

In two studies, researchers examined the importance of elevated central venous pressure (CVP) in patients with so-called cardiorenal syndromes, which are characterized by both heart failure (HF) and renal insufficiency (RI).

Investigators retrospectively studied 2557 patients who underwent right-heart catheterization at a single center in the Netherlands during a 17-year period to determine the association of CVP, renal function, and mortality. CVP was related inversely to both cardiac index and renal function (assessed by estimated glomerular filtration rate). During a median follow-up of 10.7 years, 29% of patients died. In a multivariate analysis, elevated CVP remained an independent predictor of mortality (hazard ratio, 1.03 per mm Hg in…

Reviewing Author

Kirsten E. Fleischmann, MD, MPH

Disclosures

Grant/Research SupportNational Institutes of Health

Leadership Positions in Professional SocietiesAmerican College of Cardiology/American Heart Association

Kirsten E. Fleischmann, MD, MPH

Disclosures

Grant/Research SupportNational Institutes of Health

Leadership Positions in Professional SocietiesAmerican College of Cardiology/American Heart Association