Impaired Kidney Function and Risks for CV Disease and Death

Low-risk women with GFRs <60 had elevated risk for CV-related death but not for adverse CV events, non–CV-related death, or all-cause death.

Prior research suggests that impaired kidney function is associated with elevated risks for cardiovascular (CV) disease and death from all causes (especially from CV disease). However, these studies involved people at high risk for CV disease, people with CV disease, or people with severe renal impairment. To assess this association in people without these risks, investigators analyzed data for 28,000 female health professionals who were at least 45 and free of CV disease at entry into the Women's Health Study.

Baseline blood samples were used to determine and categorize the women by glomerular filtration rate (GFR): <60 mL/minute/1.73 m² (5%), 60–74 (13%), 75–89 (29%), and ≥90 (53%). During a mean follow-up of 12 years, 1199 women had at le…

Reviewing Author

Paul S. Mueller, MD, MPH, FACP

Disclosures

Nothing to disclose

Paul S. Mueller, MD, MPH, FACP

Disclosures

Nothing to disclose

Impaired Kidney Function and Risks for CV Disease and Death

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Reviewing Author