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Inflammatory bowel disease (IBD) raises risk for venous thromboembolism, and patients hospitalized with active IBD generally receive prophylaxis against this potentially fatal complication. But risk for thromboembolism among ambulatory patients with active IBD is unknown.
British investigators used a database of ambulatory patient records to identify almost 14,000 patients with IBD and almost 72,000 matched controls who had been followed for an average of 4 years. Among controls, incidence of thromboembolism was 13.9 episodes per 1000 person-years during hospitalizations and 0.4 episodes per 1000 person-years during ambulatory periods. Patients with IBD were at significantly elevated risk for thromboembolism during hospitalizations (hazard r…