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In patients with pulmonary embolism (PE), does coexistence of detectable deep venous thrombosis (DVT) have prognostic significance? Researchers in Spain addressed this question in a prospective cohort study of emergency department patients with acute PE confirmed by imaging. All patients additionally underwent compression ultrasonography of the lower extremities.
Of 707 enrolled patients with PE, 51% had concomitant DVT. During 3 months of follow-up, all-cause mortality was significantly higher in patients with DVT than in those without DVT (15% vs. 6%). In multivariate analysis adjusting for numerous potential confounding variables, significant predictors of death were concomitant DVT (hazard ratio, 2.1), cancer (HR, 3.7) and immobilization…