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Robust data on the association between vitamin D status and long-term fracture risk are surprisingly sparse. In this population-based Swedish cohort study, researchers measured 25-hydroxyvitamin D (25[OH]D) levels in 1194 older men (mean age, 71) using a gold-standard method (high-pressure liquid chromatography–mass spectrometry) and followed them for an average of 11 years.
During follow-up, 26% of participants sustained fractures. Fracture risk was similar at all levels of 25(OH)D that were ≥16 ng/mL. Fracture risk was elevated among men with levels <16 ng/mL, but only 5% of men fell into this category, and only 3% of all fractures were potentially attributable to 25(OH)D levels <16 ng/mL. Risk for falling was not elevated among those with…