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Several organizations recommend a blood pressure (BP) goal of <130/80 mm Hg for patients with diabetes. To determine whether this goal is appropriate for patients with diabetes and known coronary artery disease (CAD), researchers conducted a secondary analysis of data from the INVEST study, a randomized trial in which hypertensive patients with CAD received β-blocker–based or calcium-channel blocker–based regimens (JW Gen Med Dec 23 2003). Researchers reported previously that overly aggressive BP lowering in these patients was associated with excess risk for adverse cardiovascular events (JW Gen Med Aug 10 2006); now, they focus on subset of 6400 INVEST patients with diabetes.
Patients were divided into three groups according to their averag…