Loading...
Most in-center hemodialysis is performed three times weekly. To determine whether more frequent dialysis leads to better outcomes, North American researchers randomized 245 chronically hemodialyzed patients to undergo either three or six in-center sessions weekly for 1 year.
Comment
Because a study of this duration has limited power to detect differences in mortality, the researchers chose two “co-primary” endpoints: (1) death or increase in left ventricular mass (determined by magnetic resonance imaging) and (2) death or decline in self-reported overall health (determined by standardized questionnaires). At 1 year, both these outcomes were significantly better with frequent dialysis than with convention…