Loading...
Previous research has suggested a relation between enterovirus infection and subsequent development of type 1 diabetes. In this systematic review and meta-analysis, investigators assessed the association between active enterovirus infection, detected using molecular methods, and development of diabetes-related islet cell autoimmunity or type 1 diabetes. Most of the patients with diabetes had recent-onset or newly diagnosed diabetes.
The analysis included 24 observational studies that involved more than 4400 patients. Most studies involved children, although some included adult participants as old as 53. Infection was diagnosed by measuring enterovirus RNA or viral protein in blood, stool, or tissue. Significant associations occurred between …