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Distinguishing between psychogenic nonepileptic seizures and epileptic seizures can be challenging. In this single-center study, researchers in Cleveland sought to identify clinical signs that might help to make this distinction. Thirty-five patients with seizure-like events underwent inpatient video electroencephalogram (EEG) monitoring; psychogenic seizures ultimately were diagnosed in 12, and epileptic seizures were diagnosed in 23 (confirmed by EEG findings during events). Epileptologists who were blinded to EEG findings watched videos of these events and recorded whether 48 potential signs of psychogenic or epileptic seizures were present or absent for each patient.
Only six signs classified type of seizure with at least 80% accuracy: T…