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Chronic kidney disease (CKD) predisposes patients to coronary heart disease, but its association with atrial fibrillation (AF) is unclear. To explore this relation, researchers used data from a large cohort study with 10,328 participants who were AF-free at baseline.
During median follow-up of about 10 years, 788 cases of incident AF were identified; declining kidney function as measured by cystatin C and albuminuria were both associated with elevated risk for incident AF. Compared with people who had estimated glomerular filtration rates (eGFRs) of ≥90 mL/minute/1.73 m2, the hazard ratios for AF were 1.3, 1.6, and 3.2 for those with eGFRs of 60–89, 30–59, and 15–29 mL/minute/1.73 m2, respectively. Macroalbuminuria and even microalbuminuria …