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Computed tomographic angiography (CTA) is used increasingly for detection of obstructive coronary disease, but do the findings predict prognosis and future adverse cardiovascular events? Investigators addressed this issue in a meta-analysis of 11 studies, each with a minimum enrollment of 100 patients and minimum follow-up of 1 year. All patients had symptoms that were suggestive of coronary artery disease.
In nine studies (total enrollment, >3500), having at least one marked stenosis (≥50%) was associated with an annualized rate of mortality, myocardial infarction, unstable angina, and revascularization of 11.9%, but revascularization accounted for 62% of the 252 events. Left main stenosis, assessed in four studies, was associated with a ha…