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Gastric bypass and biliopancreatic diversion with duodenal switch are two types of bariatric surgery; however, little data exist to compare outcomes of these procedures. In this study from Norway and Sweden, 60 patients with body-mass indexes (BMIs) of 50–60 kg/m2 were randomized to gastric bypass or duodenal switch.
At 2 years, mean weight loss was greater among duodenal switch patients than among gastric bypass patients (74 vs. 51 kg). Total cholesterol levels fell by a mean of 41 mg/dL among duodenal switch patients, but no significant decline was seen among gastric bypass patients. Both groups had significant mean reductions in LDL cholesterol levels (duodenal switch, 30 mg/dL; gastric bypass, 10 mg/dL), systolic blood pressure, diastoli…