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Iodine-induced thyroid dysfunction is well known. Because of the surge in use of angiography and computed tomography, more people are receiving iodinated contrast media (ICM), which exposes the thyroid to huge iodide loads. To shed additional light on this phenomenon, researchers conducted a retrospective case-control study based on data from a large Boston healthcare system.
Roughly 200 patients with incident hypothyroidism and 200 with hyperthyroidism from 1990–2010 were matched by several criteria (e.g., age, sex, race, renal function) with roughly 700 euthyroid patients. Each patient had to have a normal thyrotropin level on record, no prior evidence of thyroid disease or treatment, and a follow-up thyrotropin measurement from 2 weeks to…