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Intractable skin and soft-tissue (SST) abscesses caused by Staphylococcus aureus have become a scourge for adult and pediatric patients alike. Some evidence indicates that transmission from colonized household members may contribute to the high recurrence rate of these infections.
Researchers assigned children with SST S. aureus infections who were confirmed carriers to one of two treatment groups. In one group, only the child followed a 5-day decolonization regimen with topical mupirocin and chlorhexidine. In the other group, all household members were asked to follow the same regimen.
After a month, about half the index children in each group were still colonized with S. aureus, and colonization rates remained similar between groups at 3, 6…