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The ACCORD blood pressure trial showed that intensive blood pressure control (target systolic BP, <120 mm Hg), compared with standard BP control (target SBP, <140 mm Hg), was not associated with lower risk for fatal and nonfatal cardiovascular events in patients with longstanding type 2 diabetes (JW Cardiol Mar 14 2010). In this meta-analysis, investigators evaluated outcomes of treating to intensive BP targets (SBP, ≤130 mm Hg; diastolic BP, ≤80 mm Hg) or to standard BP targets (upper limits: SBP, 140–160 mm Hg; DBP, 85–100 mm Hg) in such patients.
Five randomized trials that involved more than 7300 participants (mean ages, 53–62; mean duration of diabetes, 7–10 years) were included in the analysis. Achieved BPs in intensive-target groups w…