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Patients with good-risk prostate cancers (Gleason grade 6 or 7, prostate-specific antigen [PSA] level <10, stage T1/T2) have excellent long-term outcomes following radical prostatectomy, external-beam radiotherapy, or brachytherapy. As disease-related outcomes are quite good, patients and their physicians have focused increasingly on treatment-related side effects and quality-of-life (QOL) issues to guide therapy decisions. During the past 2 decades, several relatively small case series and trials, frequently capturing single-institution patient-reported QOL outcomes, have been reported.
To assess QOL and treatment satisfaction, investigators from nine university hospitals enrolled 1201 men (median age, 63; 9% black) with previously untreate…