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In 2002, the U.S. Preventive Services Task Force (USPSTF) found that evidence was insufficient to recommend routine screening for prostate cancer (JW Jan 10 2003). In 2008, after reevaluating data on the prostate-specific antigen (PSA) test, the USPSTF revised their guidelines, based on the conclusion that, although evidence remained insufficient to assess the benefits and harms associated with screening men younger than 75, evidence did indicate that men 75 or older should not undergo screening, given that treating screen-detected prostate cancer in older men is of little or no benefit (JW Aug 26 2008).
In an update of evidence related to the USPSTF guidelines, U.S. investigators reviewed randomized controlled trials (RCTs) and meta-analyse…