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Platelet inhibitors such as aspirin, clopidogrel, and dipyridamole are common options to prevent recurrent stroke. Aspirin has been associated with a 23% lower risk for recurrence than is placebo (BMJ 2002; 324:71). Clopidogrel, an inhibitor of one of the platelet adenosine diphosphate receptors, has efficacy similar to that of aspirin in preventing recurrent events (Lancet 1996; 348:1329). Dipyridamole, a phosphodiesterase inhibitor that raises platelet cyclic adenosine monophosphate levels to inhibit platelet function, is more effective for secondary stroke prevention than is aspirin alone (JW Jun 9 2006).The last of these findings raised expectations that aspirin plus dipyridamole (A+D) would be more effective than clopidogrel for stroke…