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The limitations of computed tomography (CT) and magnetic resonance imaging (MRI) of the pelvis make radiographic assessment of patients with muscle-invasive bladder cancer problematic. Clinical staging — defined ultimately by pathologic evaluation of the bladder after cystectomy — has shown that understaging and overstaging are common when imaging (typically CT), cystoscopic exams, and pathology findings from transurethral resection of bladder tumor are used.
To date, the case has not been strong for routine use of fluorine-18 2-fluoro-2-deoxy-D-glucose (FDG) positron emission tomography (PET) as an imaging technique in bladder cancer. The clinical value of FDG-PET/CT has shown greater promise, prompting investigators to prospectively evalua…