Residual Venous Obstruction Does Not Predict Recurrent VTE

Results of a prospective cohort study and a meta-analysis suggest that the idea of performing CUS to detect RVO should be abandoned.

Almost half of all patients with unprovoked deep venous thrombosis (DVT) experience recurrent venous thromboembolism (VTE). The presence of residual venous obstruction (RVO), which can be detected by compression ultrasound (CUS), is thought to be associated with excess risk for VTE recurrence. Researchers have now conducted two studies to test this hypothesis.

In REVERSE, a multicenter prospective cohort study, investigators assessed 452 patients with a first unprovoked DVT. CUS was performed after participants completed anticoagulant therapy for 5 to 7 months. During a median follow-up of 17 months (range, 6–24 months), RVO was identified by CUS in 231 patients (51.1%). The rate of recurrent VTE was nonsignificantly higher in patients with …

Reviewing Author

David Green, MD, PhD

Disclosures

EquityNovartis

David Green, MD, PhD

Disclosures

EquityNovartis