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Although there are identifiable and potentially modifiable lifestyle risk factors for pancreatic cancer — including obesity and tobacco and alcohol use — these have only a marginal impact on the risk for developing the disease. Moreover, screening for pancreatic cancer is neither cost effective nor practical and is currently limited to high-risk individuals with a genetic predisposition for familial pancreatic cancer.
To evaluate a potential biomarker for developing pancreatic cancer, investigators conducted a prospective, case-control trial involving five large patient cohorts, which evaluated serum levels of adiponectin, a circulating hormone produced by adipose tissue that enhances insulin sensitivity and may be associated with the risk f…