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The increasing prevalence of community-acquired Staphylococcus aureus (CA-SA) infection — a hot topic in both the medical literature and the lay press — has led to questions and concerns about optimal evaluation and treatment. Investigators at Texas Children’s Hospital reviewed their experience with CA-SA infections in 126 previously healthy infants (age, ≤30 days) from 2001 to 2006.
Infants were categorized into three groups: 43 infants with pustulosis; 68 infants with cellulitis or abscess; and 15 infants with invasive infections. Fever was present at the time of or before presentation in 2%, 25%, and 60% of infants in the three groups, respectively. Blood cultures were positive in 0%, 3%, and 36%, respectively. None of 84 cerebrospinal fl…