Loading...
Confusion exists about whether single umbilical artery (SUA) is associated with congenital malformations. Researchers examined the most frequent anomalies and those most specifically associated with SUA in a cohort of nearly 20,000 consecutive newborns with congenital malformations from a Spanish collaborative study.
In a comparison of infants with congenital malformations who did and did not have SUA, the authors found that bilateral renal agenesis, imperforate anus, unilateral renal agenesis, and vertebral defects were 8 to 10 times more common among the infants with SUA. Cardiovascular anomalies were the most frequent malformations in infants with and without SUA, but these anomalies were only 2.5 times more common in infants with SUA tha…