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Chronic fatigue syndrome (CFS) is a disabling condition at any age, but some studies exclude children younger than 12 years. To describe CFS in younger children, investigators in the U.K. identified 178 children (age, <18 years) who were diagnosed with CFS from 2004 to 2007, based on the Royal College of Paediatrics and Child Health’s definition of “generalized fatigue persisting after routine tests and investigations have failed to identify an obvious underlying cause.”
At the time of assessment, 32 children (22 girls) were younger than 12 years (3 were younger than 5 years, and the youngest was age 2 years). Standardized inventories of fatigue, disability, anxiety, pain, and school absence showed that children younger than 12 years had the…