No Increase in Long-Term Mortality After Simple Febrile Seizures

In a large population-based study, children with simple febrile seizures did not have higher risk for death, but children with complex seizures did.

Mortality risk associated with febrile seizures in children is uncertain. Investigators examined this risk in a population-based study of more than 1.6 million Danish children born in 1977 through 2004 and followed for as long as 28 years (23.1 million person-years).

Compared with children without histories of febrile seizures, the 55,215 children with a first febrile seizure between ages 3 months and 5 years had mortality rate ratios (MRRs) that were 80% higher during the first postictal year, 90% higher during the second year, and similar to the general population thereafter. Risk for sudden unexplained death during the 2 years after a first febrile seizure (either simple or complex) was five times higher than in the general population, al…

Reviewing Author

F. Bruder Stapleton, MD

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Consultant/Advisory BoardCareer Physician

Editorial BoardsUpToDate

Leadership Positions in Professional SocietiesAmerican Society of Pediatric Nephrology Foundation (Chair)

F. Bruder Stapleton, MD

Disclosures

Consultant/Advisory BoardCareer Physician

Editorial BoardsUpToDate

Leadership Positions in Professional SocietiesAmerican Society of Pediatric Nephrology Foundation (Chair)

No Increase in Long-Term Mortality After Simple Febrile Seizures

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Reviewing Author