Improving Glycosylated Hemoglobin Levels in Children with Diabetes

The goal for patients with type 1 diabetes is to have normal glycosylated hemoglobin (HbA_1c) levels. Investigators randomized 322 patients with type 1 diabetes (HbA_1c level, 7%–10%) who were treated with intensive insulin therapy to management with continuous glucose monitoring or home monitoring with a blood glucose meter. Patients were grouped by age (8–14 years, 15–24 years, ≥25 years).

After 26 weeks of treatment, change in HbA_1c level (the primary outcome) was significantly greater in patients aged ≥25 in the continuous-monitoring group, compared with those in the conventional-monitoring group (mean difference in change, 0.53%). Older patients in the continuous-monitoring group also had significant improvements in all secondary outcomes…