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Whether adolescent body-mass index (BMI) is linked to adverse health outcomes in adulthood — independent of adult BMI — is uncertain. Investigators prospectively followed more than 37,000 men in the Israeli army from age 17 years to age 25 to 45 to identify incident cases of angiography-proven coronary heart disease (CHD) and type 2 diabetes (2 fasting plasma glucose levels ≥126 mg/dl).
During a mean follow-up of 17 years, 327 cases of CHD and 1173 incident cases of diabetes were documented. In a multivariate analysis (adjusted for age, family history, blood pressure, physical activity, triglycerides, and glucose), elevated adolescent BMI (>70th percentile) was associated with significantly increased risk for incident diabetes, but the assoc…