Henoch-Schönlein Purpura After Influenza Vaccination

This complication is rare and self-limited in most instances.

Henoch-Schönlein purpura (HSP) is defined as palpable purpura with lower extremity involvement and at least one of the following features: diffuse abdominal pain, arthralgia or arthritis, hematuria or proteinuria, or IgA deposits in the glomeruli. HSP is the most common systemic vasculitis in childhood and may be triggered by drugs and infections as well as vaccinations. Researchers report the first case series of HSP after influenza vaccination.

Four children (age range, 4–7 years) in Japan developed HSP following seasonal or pandemic influenza vaccination in October and November 2009. All children developed symptoms 1 to2 days after vaccination. In three children symptoms resolved after 1 to 4 weeks, without renal manifestations. However, …

Reviewing Author

F. Bruder Stapleton, MD

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Consultant/Advisory BoardCareer Physician

Editorial BoardsUpToDate

Leadership Positions in Professional SocietiesAmerican Society of Pediatric Nephrology Foundation (Chair)

F. Bruder Stapleton, MD

Disclosures

Consultant/Advisory BoardCareer Physician

Editorial BoardsUpToDate

Leadership Positions in Professional SocietiesAmerican Society of Pediatric Nephrology Foundation (Chair)

Henoch-Schönlein Purpura After Influenza Vaccination

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Reviewing Author