Asthmatic Children with Viral Respiratory Infection Symptoms Require More β2-Agonists

At 24 hours, asthmatic children with VRI symptoms had received four more doses on average than those with no VRI symptoms.

As many as 60% to 85% of acute asthma exacerbations are associated with viral respiratory infections (VRIs). Investigators examined the effect of VRI on clinical response to treatment with inhaled salbutamol, oral prednisolone, and supplemental oxygen in 218 children (mean age, 6.6 years) examined in an emergency department in Australia for acute asthma attacks. Most children (77%) had symptoms of VRI (defined as a combination of symptoms including runny nose, sore throat, and cough).

No significant differences were observed in asthma severity scores, oxygen saturation levels, or serum immunoglobulin E concentrations between children with and without VRI symptoms. Viruses were identified in 64% of children in whom nasal aspirates were collec…

Reviewing Author

F. Bruder Stapleton, MD

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Consultant/Advisory BoardCareer Physician

Editorial BoardsUpToDate

Leadership Positions in Professional SocietiesAmerican Society of Pediatric Nephrology Foundation (Chair)

F. Bruder Stapleton, MD

Disclosures

Consultant/Advisory BoardCareer Physician

Editorial BoardsUpToDate

Leadership Positions in Professional SocietiesAmerican Society of Pediatric Nephrology Foundation (Chair)

Asthmatic Children with Viral Respiratory Infection Symptoms Require More β₂-Agonists

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Reviewing Author