High levels of urinary bisphenol A measured during gestation were associated with anxious and depressed behavior and poorer emotional control in children at age 3 years.
Bisphenol A (BPA) is used to make polycarbonate plastics and is widely found in food and drink packaging. Virtually everyone in industrialized countries is exposed to BPA. Investigators in Ohio measured urine BPA levels in a prospective birth cohort of 244 mothers and their 3-year-old children. Maternal urine samples were collected at 16 and 26 weeks' gestation and at delivery, and children's urine samples were collected at ages 1, 2, and 3 years.
Mean gestational BPA concentrations in mothers correlated with childhood behavior and executive function as measured on validated assessment tools at age 3 years. In analysis adjusted for confounders, maternal gestational BPA concentrations were positively associated with scores on measures of anxi…
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DisclosuresGrant/Research SupportNIH Institutional Clinical and Translational Science Award; Agency for Healthcare Research and Quality National Center for Pediatric Practice Based Research Learning; Patient-Centered Outcomes Research Institute
Editorial BoardsCurrent Problems in Pediatric Adolescent Healthcare
Leadership Positions in Professional Societies College of Physicians of Philadelphia (Board of Trustees)
DisclosuresGrant/Research SupportNIH Institutional Clinical and Translational Science Award; Agency for Healthcare Research and Quality National Center for Pediatric Practice Based Research Learning; Patient-Centered Outcomes Research Institute
Editorial BoardsCurrent Problems in Pediatric Adolescent Healthcare
Leadership Positions in Professional Societies College of Physicians of Philadelphia (Board of Trustees)