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Vesicoureteral reflux (VUR) is the most common urinary tract abnormality in children and is associated with recurrent urinary tract infection (UTI). Although controversial, surgical correction of VUR might be considered to protect kidney function in children with high-grade VUR who experience recurrent febrile UTI. Endoscopic correction with subureteral intravesical injection of a tissue augmenting substance is a newer, less-invasive alternative treatment. Researchers examined the risk for febrile UTI following successful endoscopic correction of intermediate or high-grade VUR in 1271 consecutive children (68% girls).
During a mean follow-up of 7.6 years, 73 children (5.7%) developed febrile UTI following successful elimination of VUR; 55% o…