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Milk allergy affects 2% to 3% of U.S. children and is the most common childhood food allergy. Previous studies indicated that 75% of children “outgrow” this allergy, but newer studies suggest much lower rates of resolution. Researchers examined the natural history of milk allergy in 293 children from age 3 to 15 months to a median age of 63 months.
By age 5 years, milk allergy fully resolved in only 53% of patients. Another 21% could tolerate milk in baked goods. Larger skin-prick test size, higher milk-specific IgE (sIgE) level, and moderate-to-severe eczema at baseline were associated with lower likelihood of resolution.
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Unfortunately, only about half the children with milk all…