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Among women who use hormonal contraception for family planning, poor adherence to pill regimens remains a significant problem. These 2 new hormonal contraceptives may provide women with effective alternatives.
In a randomized, open-label, manufacturer-sponsored trial conducted at 45 centers in the U.S. and Canada, investigators compared 20-cm2, 7-day, combination contraceptive patches with triphasic combination oral contraceptives (OCs). Healthy women (age range, 18 to 45) were assigned to receive patches (812 participants) or OCs (605) for 6 or 13 cycles (21-day hormone plus 7-day hormone-free phases). Failure rates were comparable: Among patch users, there were 4 method-failure pregnancies and 1 user-failure pregnancy; among OC users, ther…