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The risk for multiple gestations after in vitro fertilization (IVF) increases with the number of embryos transferred, but so does the pregnancy rate. Thus, clinicians and patients must choose between the possibilities of multiple births and a failed IVF cycle. In this multicenter, blinded trial, Swedish researchers randomized 661 women (age, <36) with multiple good-quality embryos to have two embryos transferred during one IVF cycle (double-transfer group), or to have one embryo transferred and others cryopreserved and one subsequently transferred if the fresh-embryo transfer did not result in a live birth (single-transfer group).
Six women in the double-transfer group and 25 in the single-transfer group did not undergo transfer, due to medi…