Disappointing Data on Computer-Aided Detection for Screening Mammography

CAD did not improve the sensitivity of screening mammograms and was associated with higher recall and biopsy rates.

In the decade since the FDA approved the use of computer-aided detection (CAD) for screening mammography, some breast-imaging centers have implemented CAD to improve the performance of screening mammograms. In a multicenter study supported by U.S. federal agencies and the American Cancer Society, investigators evaluated the effect of CAD on screening mammography among 222,135 women (age ≥40) who underwent mammography from 1998 to 2002 at 43 clinical sites (429,345 mammograms), including 2351 women diagnosed with breast cancer within 1 year of screening.

Seven sites implemented CAD during the study period. After implementation, diagnostic specificity declined from 90.2% to 87.2% (P<0.001), positive predictive value declined from 4.1% to 3.2% …

Reviewing Author

Andrew M. Kaunitz, MD

Disappointing Data on Computer-Aided Detection for Screening Mammography

Topics

Reviewing Author