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Several studies have shown that condom use at sexual debut is associated with continued condom use. To assess the relation between condom use at first vaginal coitus with rates of sexually transmitted infections (STIs), investigators analyzed data from more than 4000 sexually active participants (52% women; average age of all participants at sexual debut, 15.2) in the National Longitudinal Study of Adolescent Health. Beginning in 1994, the investigators conducted three waves of in-home interviews; at the time of the third wave (when the average age of participants was 22.2), urine samples were collected and tested with ligase chain reaction (LCR) for Neisseria gonorrhoeae and Chlamydia trachomatis DNA.
In comparisons adjusted for factors suc…