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Approximately 2% of people have psoriasis, a chronic inflammatory skin disease. Chronic inflammation from adipose tissue might pose an increased risk for the disorder. To determine the relation between adiposity and incident psoriasis, researchers studied nearly 79,000 women who were psoriasis free at enrollment in the Nurses’ Health Study II and for whom self-reported BMI, weight gain since age 18, waist and hip circumference, and waist-hip ratio were obtained.
In biennial health questionnaires, 862 women reported physician-diagnosed psoriasis since 1991. When women with BMIs of 21.0–22.9 were used as the reference group, the adjusted relative risk for psoriasis increased progressively with higher BMI. Women who were overweight (BMI, 25.0–2…