Loading...
Osteoporotic fractures are on the rise globally. In the international Observational Study of Severe Osteoporosis, an industry-sponsored 12-month prospective study, researchers compared fracture incidence and health-related quality of life (HR-QOL) in postmenopausal women who had previous fragility fractures and in those who did not. Inadequate clinical outcome of osteoporosis therapy was defined either as a fragility fracture despite osteoporosis treatment for at least 1 year or as nonadherence to medication.
During follow-up, 9% of participants experienced fractures. Compared with women who had no histories of fracture, those who had fractures within 1 year before study entry were almost twice as likely to sustain incident fractures (hazard…