Assisted Reproduction for Couples with HIV-Positive Male Partners

IVF with intracytoplasmic sperm injection using washed sperm is safe and effective.

When an HIV-positive man and an HIV-negative woman seek to have a child through in vitro fertilization with intracytoplasmic sperm injection (IVF-ICSI), the sperm are first washed to remove any virus. A university-based reproductive endocrinology and fertility group in New York City now reports its 10-year experience with IVF-ICSI using washed sperm, and the results are reassuring.

In all, 420 treatment cycles (355 with fresh embryos from donor or nondonor oocytes and 65 with frozen embryos) were initiated in 181 HIV-serodiscordant couples, resulting in 161 clinical pregnancies in 128 couples. The overall clinical pregnancy rate per embryo transfer was 46%, and the ongoing or delivered pregnancy rate per transfer was 39%. Fully 41% of pregna…

Reviewing Author

Robert W. Rebar, MD

Disclosures

Consultant/Advisory BoardMyovant Sciences, Inc.

Editorial BoardsEndoText; Clinical OB/GYN Alert

Leadership Positions in Professional SocietiesAmerican Society for Reproductive Medicine (Member, Ethics Committee)

Robert W. Rebar, MD

Disclosures

Consultant/Advisory BoardMyovant Sciences, Inc.

Editorial BoardsEndoText; Clinical OB/GYN Alert

Leadership Positions in Professional SocietiesAmerican Society for Reproductive Medicine (Member, Ethics Committee)

Assisted Reproduction for Couples with HIV-Positive Male Partners

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Reviewing Author