Ovulation Can Occur During the Menopausal Transition

During perimenopause, 25% of cycles longer than 60 days were ovulatory.

To obtain additional information about risk for conception during the menopausal transition, investigators collected daily urine specimens from 108 women (age range, 25–58) and measured levels of follicle-stimulating hormone (FSH), luteinizing hormone (LH), estrone glucuronide (E1G), and pregnanediol glucuronide (PDG, a metabolite of progesterone) for 6-month intervals during each of 5 consecutive years. Participants recorded menstrual bleed data to determine cycle length.

As expected, the percentage of anovulatory cycles rose during the menopausal transition, with >60% of cycles being anovulatory by late perimenopause. However, 25% of cycles longer than 60 days were ovulatory. As women progressed through the menopausal transition, the mean …

Reviewing Author

Robert W. Rebar, MD

Disclosures

Consultant/Advisory BoardMyovant Sciences, Inc.

Editorial BoardsEndoText; Clinical OB/GYN Alert

Leadership Positions in Professional SocietiesAmerican Society for Reproductive Medicine (Member, Ethics Committee)

Robert W. Rebar, MD

Disclosures

Consultant/Advisory BoardMyovant Sciences, Inc.

Editorial BoardsEndoText; Clinical OB/GYN Alert

Leadership Positions in Professional SocietiesAmerican Society for Reproductive Medicine (Member, Ethics Committee)

Ovulation Can Occur During the Menopausal Transition

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Reviewing Author