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Massive blood loss is common at delivery in women who have placenta accreta, with maternal mortality as high as 7%. In a retrospective cohort study, investigators reviewed all pathologically confirmed cases of placenta accreta at a single U.S. hospital from 1990 to 2008. Of 99 such cases, placenta accreta was diagnosed prior to delivery in 62 women, who underwent planned cesarean hysterectomy without attempted removal of the placenta at 34 to 35 weeks' gestation (after betamethasone treatment).
For pregnancies in which placenta accreta was diagnosed antenatally, delivery was associated with transfusion of fewer units of packed red blood cells (4.7 vs. 6.9; P=0.02) but longer length of hospitalization (7.4 vs. 5.5 days; P=0.01). More admissio…