Does Aspirin Extend Breast Cancer Survival?

Aspirin use was associated with lower risk for distant recurrence and breast cancer–related death.

Preclinical studies indicate that aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) can inhibit breast cancer metastasis. Investigators used data from the Nurses' Health Study (NHS) to assess whether aspirin use by women who have received breast cancer diagnoses affects survival and risk for distant recurrence. Among 4164 participants with breast cancer who provided information regularly on aspirin use as part of NHS questionnaires, 400 distant recurrences and 341 deaths from breast cancer (all of which occurred in women with recurrences) were reported during the study period.

Aspirin use was associated with lower risk for breast cancer–related death. Adjusted relative risk (RR) for breast cancer–related death was 0.88 for past…

Reviewing Author

Andrew M. Kaunitz, MD

Disclosures

RoyaltiesUpToDate

Grant/Research SupportMerck, Mithra, Medicines360

Editorial BoardsContraception; Menopause; Contraceptive Technology Update; OBG Management; Medscape OB/GYN & Women’s Health

Andrew M. Kaunitz, MD

Disclosures

RoyaltiesUpToDate

Grant/Research SupportMerck, Mithra, Medicines360

Editorial BoardsContraception; Menopause; Contraceptive Technology Update; OBG Management; Medscape OB/GYN & Women’s Health

Does Aspirin Extend Breast Cancer Survival?

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Reviewing Author