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Children conceived by in vitro fertilization (IVF) are at risk for prematurity, adverse perinatal outcomes, and certain birth defects. But just how well do IVF children develop cognitively? Investigators in Iowa compared scores of 423 IVF children (age range, 8–17 years) on the Iowa Tests of Basic Skills/Educational Development with those of comparator children matched with each IVF child by sex, grade level, calendar year of testing, and school district.
Most parents of IVF children were white, college educated or higher, and married at study entry. Almost half (48%) of IVF children were singletons, 42% were twins, and 10% were triplets. Test scores of IVF children were higher than national mean scores (P<0.0001) as well as scores of their …