Are In Vitro Fertilization Success Rates Lower in Overweight Men?

Retrospective analysis says yes, except when intracytoplasmic sperm injection is used.

Prevalence of obesity is rising worldwide, and the detrimental effects of this condition on female fertility have become apparent. Moreover, obese women with overweight or obese partners have as much as twofold lower fertility than do obese women with normal-weight partners. In a retrospective study at a single center, investigators tested the hypothesis that in vitro fertilization (IVF) success rates would be negatively affected in men with body-mass index (BMI) ≥25 kg/m².

Of 290 analyzed cycles, 115 (40%) resulted in clinical pregnancies. This rate was 34% when male BMI was ≥25 and 53% when male BMI was <25. The effect of high male BMI was independent of female BMI or number of embryos transferred. When intracytoplasmic sperm injection (IC…

Reviewing Author

Robert W. Rebar, MD

Disclosures

Consultant/Advisory BoardMyovant Sciences, Inc.

Editorial BoardsEndoText; Clinical OB/GYN Alert

Leadership Positions in Professional SocietiesAmerican Society for Reproductive Medicine (Member, Ethics Committee)

Robert W. Rebar, MD

Disclosures

Consultant/Advisory BoardMyovant Sciences, Inc.

Editorial BoardsEndoText; Clinical OB/GYN Alert

Leadership Positions in Professional SocietiesAmerican Society for Reproductive Medicine (Member, Ethics Committee)

Are In Vitro Fertilization Success Rates Lower in Overweight Men?

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Reviewing Author