Emotional Distress Does Not Seem to Affect Chances of Pregnancy with IVF

Pretreatment worry, tension, and depression were not associated with in vitro fertilization outcomes.

Infertile women who undergo in vitro fertilization (IVF) are often emotionally labile. Does emotional distress affect the chances of pregnancy in a single cycle of IVF? Investigators conducted a meta-analysis that included 14 prospective studies and 3583 infertile women who completed a validated questionnaire to measure anxiety or depression before a cycle of IVF with or without intracytoplasmic sperm injection. Those who achieved pregnancies (defined based on positive pregnancy tests, positive fetal heart scans, or live births) were compared with those who did not.

Pretreatment emotional distress was not associated with cycle outcomes. Various subgroup analyses aimed at examining prior IVF cycles, timing of emotional assessment, and composi…

Reviewing Author

Robert W. Rebar, MD

Disclosures

Consultant/Advisory BoardMyovant Sciences, Inc.

Editorial BoardsEndoText; Clinical OB/GYN Alert

Leadership Positions in Professional SocietiesAmerican Society for Reproductive Medicine (Member, Ethics Committee)

Robert W. Rebar, MD

Disclosures

Consultant/Advisory BoardMyovant Sciences, Inc.

Editorial BoardsEndoText; Clinical OB/GYN Alert

Leadership Positions in Professional SocietiesAmerican Society for Reproductive Medicine (Member, Ethics Committee)

Emotional Distress Does Not Seem to Affect Chances of Pregnancy with IVF

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Reviewing Author