Revisiting the Bottle: Alcohol and Breast Cancer Risk

Low levels of alcohol consumption are associated with moderately elevated risk, but benefits of alcohol should also be considered.

Moderate alcohol consumption has been associated with modestly elevated risk for breast cancer, perhaps mediated by increases in circulating estrogen levels (JW Womens Health Mar 26 2009), but the effects of low-level consumption (as well as lifetime drinking patterns) remain to be determined. Now, investigators have analyzed Nurses' Health Study data from 1980 to 2008. During this period, >74,000 participants (94% non-Latina white) provided seven updates about their alcohol consumption; 7690 cases of invasive breast cancer were diagnosed in this cohort.

In analyses adjusted for other breast cancer risk factors (e.g., estrogen therapy), low levels of alcohol consumption (equivalent to 3–6 glasses of wine weekly) were associated with minimall…

Reviewing Author

Andrew M. Kaunitz, MD

Disclosures

RoyaltiesUpToDate

Grant/Research SupportMerck, Mithra, Medicines360

Editorial BoardsContraception; Menopause; Contraceptive Technology Update; OBG Management; Medscape OB/GYN & Women’s Health

Andrew M. Kaunitz, MD

Disclosures

RoyaltiesUpToDate

Grant/Research SupportMerck, Mithra, Medicines360

Editorial BoardsContraception; Menopause; Contraceptive Technology Update; OBG Management; Medscape OB/GYN & Women’s Health

Revisiting the Bottle: Alcohol and Breast Cancer Risk

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Reviewing Author