Large Uterine Fibroids Linked with Adverse Obstetric Outcomes

Fibroids larger than 5 cm were associated with earlier delivery and with maternal blood transfusion.

Uterine fibroids are common in women of reproductive age. In a retrospective cohort study, researchers in Detroit compared obstetric outcomes in 95 women with singleton pregnancies and fibroids (identified by routine ultrasound before 22 weeks' gestation) with outcomes in 95 age-matched women without fibroids.

Of the 95 women with fibroids, 42 (44%) had at least one fibroid measuring >5 cm in diameter. Those 42 women delivered, on average, significantly earlier (36.5 weeks) than the 53 women with smaller fibroids (38.4 weeks) and the 95 controls (38.6 weeks). Mean blood loss at delivery was also greatest among women with large fibroids, necessitating significantly more transfusions in that group than in the other two groups (12.2% vs. about …

Reviewing Author

Robert W. Rebar, MD

Disclosures

Consultant/Advisory BoardMyovant Sciences, Inc.

Editorial BoardsEndoText; Clinical OB/GYN Alert

Leadership Positions in Professional SocietiesAmerican Society for Reproductive Medicine (Member, Ethics Committee)

Robert W. Rebar, MD

Disclosures

Consultant/Advisory BoardMyovant Sciences, Inc.

Editorial BoardsEndoText; Clinical OB/GYN Alert

Leadership Positions in Professional SocietiesAmerican Society for Reproductive Medicine (Member, Ethics Committee)

Large Uterine Fibroids Linked with Adverse Obstetric Outcomes

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Reviewing Author